منابع مشابه
Physiologic cardiac hypertrophy corrects contractile protein abnormalities associated with pathologic hypertrophy in rats.
To evaluate the combined effects of cardiac overload imposed by hypertension and by chronic exercise, male and female rats were made hypertensive by unilateral renal artery stenoses and made to exercise in an 8-10-wk swimming program. Sedentary normotensive animals, sedentary hypertensive animals and normotensive animals exposed to the swimming program were also studied. Hypertension was associ...
متن کاملLocal insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice.
In the present study we determined the long-term effects of persistent, local insulin-like growth factor I (IGF-I) expression on cardiac function in the SIS2 transgenic mouse. Cardiac mass/tibial length was increased in SIS2 mice by 10 wk of age; this cardiac hypertrophy became more pronounced later in life. Peak aortic outflow velocity, a correlate of cardiac output, was increased at 10 wk in ...
متن کاملGenetic Expression Profiles During Physiologic and Pathologic Cardiac Hypertrophy and Heart Failure in Rats
Cardiac hypertrophy is a complex and non-homogenous response to various stimuli. In this study, we used high-density oligonucleotide microarray to examine gene expression profiles during physiologic hypertrophy, pathologic hypertrophy, and heart failure in Dahl salt-sensitive rats. There were changes in 404/3160 and 874/3160 genes between physiologic vs. pathologic hypertrophy and the transitio...
متن کاملGlial cells under physiologic and pathologic conditions.
Glial cells have long been considered to play roles in the nervous system that are unexciting compared with those of neurons. They provide neurons with nutrients, guide migrating neurons and their precursors during development, and dispose of the brain's "waste." Recent evidence, however, suggests that glial cells play more sophisticated, neuronlike roles. They integrate neuronal input, modulat...
متن کاملvariable ventilation stochastic or physiologic
variability of tidal volume and respiratory rate in normally breathing man has long been demonstrated [1]. however because of lack of knowledge and technology primary ventilators could only deliver a fixed tidal volume in a fixed rate the so called volume controlled ventilation (vcv). vcv was volume preset time triggered and cycled and there was no synchronization with patient’s breaths. at tha...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 1983
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/4.suppl_a.29